Dudley Chase (December 30, 1771-February 23, 1846) was a United States Senator from Vermont.
He graduated from Dartmouth College in 1791, studied law, and was admitted to the bar in 1793. He worked as a prosecuting attorney for Orange County, Vermont from 1803-1812.
He served as a member of the Vermont House of Representatives from 1805-1812 and speaker from 1808-1812.
Chase was elected as a Democratic Republican to the U.S. Senate in 1813 and again as an Anti-Jacksonian in 1825.
Dudley Chase was an uncle of Salmon P. Chase (Treasury Secretary, 1861-1864 and Chief Justice of the United States, 1864-1873) and Dudley Chase Denison (a U.S. Representative from Vermont.)