Edward Hempstead (June 3, 1780 - August 10, 1817) was an American lawyer, pioneer, and one of the early settlers in the new Louisiana Purchase in 1805. He was the delegate in the U.S. House for the Missouri Territory from 1812 to 1814.
Hempstead died after an accident when he was thrown from his horse on August 4, 1817. He died of his injuries six days later at his home in St. Louis, Missouri, and is buried in the Bellefontaine Cemetery there. Hempstead County, Arkansas is named in his honor.