Houston Antwine (born April 11, 1939 in Louise, Mississippi) an American college and professional football player from Southern Illinois University, was drafted by the American Football League's Houston Oilers, then traded to the Boston Patriots in 1961. He is in the Southern Illinois University Athletic Hall of Fame. A former NAIA wrestling champion, as a defensive tackle, the stocky "Twine" was nearly impossible to move out of the middle.
Antwine was cited by fellow Hall of Famer Billy Shaw as one of the American Football League's best pass rushers, athletic and very quick on his feet. He usually drew double-team blocking. He was an American Football League All-Star six straight years, from 1963 through 1968, was named to the All-Time All-AFL Team.