James Wolfenden (July 25, 1889 - April 8, 1949) was a Republican member of the U.S. House of Representatives from Pennsylvania.
James Wolfenden was born in Cardington, PA. He attended Friends' Central School and Penn Charter Academy in Philadelphia, PA. He was engaged in the manufacture of cotton and woolen goods in Cardington, PA.
He was elected to the 70th Congress as a Republican to fill the vacancy caused by the death of Thomas S. Butler. He was reelected to the 71st Congress in 1928 and served until January 3, 1947. He did not run in 1946. He died in Philadelphia, PA.