Born in Paris, France, she was the daughter of a musician and actress Bulle Ogier. Pascale Ogier too chose an acting career, first with appearances on stage. In 1982, she and her mother co-wrote and starred in director Jacques Rivette's film, Le Pont du Nord.

For her performance in the Eric Rohmer film, Les Nuits de la Pleine Lune (Full Moon in Paris), Pascale Ogier was nominated for a César Award for Best Actress and won the best actress award at the 1984 Venice Film Festival. Shortly afterwards, at 25, on the day before she was to celebrate her 26th birthday, Pascale Ogier died of a heart attack.

Pascale Ogier is buried in the Père Lachaise Cemetery in Paris.