John Hughes is the name of:
John Hughes (archbishop) (1797-1864), American Roman Catholic
John Hughes (English politician), Member of Parliament
John Hughes (film director) (born 1950), film director, writer, and producer
John 'Yogi' Hughes, footballer - Celtic F.C.
John Hughes (footballer), retired footballer & manager of Falkirk F.C.
John Hughes (businessman), Welsh businessman, developer in Ukraine
John Hughes (programming), academic & writer on functional programming
John Ceiriog Hughes (1832-1887), Welsh poet
John Hughes (British diplomat), a British diplomat and current Ambassador to Argentina
John Hughes (writer), an Australian writer and essayist